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Let us now take the half life of popular anabolic steroids and their derivatives into the accountto investigate whether they have a significant impact on the risk of cardiovascular disease." Lead investigator Dr. Paul Nesmith, MD, the senior vice president of Clinical Research and Innovation at the National Cancer Institute and a professor of medicine and toxicology at the John Hopkins University School of Medicine, said he and his colleagues wanted to know if the long-term use of the drugs could potentially affect a woman's risk of a future cardiovascular event. "I had heard the concerns about the use of steroids but had never seen any numbers to support them," he said. "What we found surprised us. When we included the data and the fact that the compounds we studied are commonly used in professional sports, we found they were associated with a significantly increased risk of heart disease. That's the conclusion we reached, but I'd like to expand on it before I publish our paper." He also said the team's data supports some of the concerns they and others have raised about the long-term use of steroids, particularly related to growth hormone effects. "In the future, studies should use higher quality data, including data from different populations, to determine if there is an association or not. When the data is from an individual, you need to know what his genetic background is, and then to figure out where the steroids are coming from -- is it from the gym, is from the athlete, how much has he been training, and what else is involved in the process." Nesmith stressed that the potential risk of a cardiovascular event with long-term use of the drugs was extremely small in the current study. "For instance, we took steroids for 25 years," he said. "By my calculations, you'd need to take the same amount of steroids, 24 a day, for nearly 20 years before it would lead to a cardiovascular event." Similar articles: